Juventus said they remain convinced of the Super League's "legitimacy" as they announced an annual loss of nearly €210 million on Friday.
Jose Mourinho's 1,000th game as a manager ended with a trademark celebratory sprint down the touchline as Roma beat Sassuolo.
AC Milan's Zlatan Ibrahimovic scored on his return from a four-month injury layoff as they beat Lazio 2-0 at San Siro on Sunday.
Sampdoria twice fought back from behind to hold Inter Milan to a 2-2 draw on Sunday, who dropped points for the first time this season.
Dusan Vlahovic scored two penalties to earn Fiorentina a 2-1 win away to Atalanta in Serie A on Saturday.
Napoli piled more misery on Juventus on Saturday as Kalidou Koulibaly's late winner clinched a 2-1 comeback victory.
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Arsenal have signed Bologna defender Takehiro Tomiyasu while right-back Hector Bellerin has left to join Real Betis on loan, the club announced.
Cristiano Ronaldo has signed for Manchester United for a second time, it was confirmed on Tuesday.
Juventus have re-signed forward Moise Kean following the departure of Cristiano Ronaldo to Manchester United.
Juventus said goodbye to Cristiano Ronaldo on Tuesday, ahead of official confirmation from Manchester United of his return to Old Trafford.
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Striker Oliver Giroud's first goals for AC Milan helped them to a comfortable 4-1 victory over Cagliari on Sunday as Stefano Pioli's team continued
Tammy Abraham's first goal for AS Roma helped his new side cruise to a 4-0 victory at promoted Salernitana on Sunday.
Juventus coach Massimiliano Allegri said his team cannot think about Cristiano Ronaldo and must turn things around after their shock loss.
Lacklustre Juventus began life without Cristiano Ronaldo by suffering a shock 1-0 defeat at home to promoted Empoli in Serie A on Saturday.
Ciro Immobile's hat-trick inspired Lazio to a 6-1 thrashing of Spezia as the Rome club made it two wins from two at the start of the new season.
Substitute Joaquin Correa had a debut to remember as his late double earned Inter Milan a 3-1 win at Hellas Verona in Serie A on Friday.