A stoppage-time winner from Lorenzo Pellegrini sealed a 4-3 Serie A win for AS Roma against Spezia on Saturday.
Roma are leading the race to sign USMNT right-back Bryan Reynolds, sources have told ESPN.
AS Roma manager Paulo Fonseca said he was unaware of a substitutions mix-up in Tuesday's Coppa Italia defeat by Spezia after making six changes.
Two goals from Luis Alberto helped Lazio earn a 3-0 victory over third-placed AS Roma in the city derby on Friday.
Juventus and Roma are among the clubs interested in signing American teenager Bryan Reynolds, sources have told ESPN.
Lazio manager Simone Inzaghi and his Roma counterpart Paulo Fonseca have lamented the absence of fans in Friday's derby.
Lazio coach Simone Inzaghi said securing a third successive victory in Friday's Rome derby could revitalise his stuttering side's Serie A season.
Gianluca Mancini's late goal earned AS Roma a 2-2 draw at home to Inter Milan on Sunday which left the visitors three points behind leaders AC Milan
Understanding how Inter Milan play will not make it any easier to beat them, AS Roma coach Paulo Fonseca said on the eve of Sunday's Serie A showdow
Borja Mayoral scored twice including a wonderful long-range strike as AS Roma brushed aside bottom team Crotone 3-1 in Serie A on Wednesday.
Veteran striker Edin Dzeko scored a late winner to earn Roma a battling 1-0 win over Sampdoria in Serie A on Sunday.