Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of Premier League fixtures.
And as you plan your fantasy team for the next gameweek, check out the Expected XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All Expected XIs and injury news powered by Rotowire, subject to updates.)
Brentford v Tottenham Hotspur
Gtech Community Stadium
Sunday, 2 p.m. GMT / 9 a.m. ET
Latest Brentford team news
Expected Lineup:
GK Mark Flekken
LB Keane Lewis-Potter | CB Nathan Collins | CB Sepp van den Berg | RB Kristoffer Ajer
DM Vitaly Janelt | DM Christian Nørgaard
LW Kevin Schade | AM Mikkel Damsgaard | RW Bryan Mbeumo
ST Yoane Wissa
Injury/suspension updates:
Josh Dasilva, M, knee, OUT, estimated return Feb. 15
Rico Henry, M/D, hamstring, OUT, estimated return Feb. 15
Aaron Hickey, M/D, hamstring, OUT, estimated return May. 18
Igor Thiago, F, infection, DOUBT
Christian Nørgaard, M, undisclosed, DOUBT
Gustavo Nunes, F/M, back, DOUBT
Ethan Pinnock, D, hamstring, DOUBT
Kevin Schade, F/M, head, DOUBT
Latest Tottenham Hotspur team news
Expected Lineup:
GK Antonin Kinsky
LB Archie Gray | CB Ben Davies | CB Radu Dragusin | RB Pedro Porro
CM Rodrigo Bentancur | CM Lucas Bergvall | CM Pape Matar Sarr
FWL Son Heung-Min | ST Richarlison | FWR Dejan Kulusevski
Injury/suspension updates:
Destiny Udogie, D, hamstring, OUT, estimated return Feb. 25
Radu Dragusin, D, knee, DOUBT
Brennan Johnson, F, calf, OUT, estimated return Feb. 16
James Maddison, F/M, calf, OUT, estimated return Feb. 22
Wilson Odobert, F/M, hamstring, OUT, estimated return Feb. 15
Cristian Romero, D, quadriceps, OUT, estimated return Feb. 16
Dominic Solanke, F, knee, OUT, estimated return Mar. 8
Djed Spence, M/D, undisclosed, DOUBT
Guglielmo Vicario, G, ankle, OUT, estimated return Feb. 25
Timo Werner, F/M, hamstring, DOUBT
Manchester United v Crystal Palace
Old Trafford
Sunday, 2 p.m. GMT / 9 a.m. ET
Latest Manchester United team news
Expected Lineup:
GK André Onana
CB Matthijs de Ligt | CB Harry Maguire | CB Lisandro Martínez
LM Noussair Mazraoui | CM Bruno Fernandes | CM Manuel Ugarte | RM Diogo Dalot
AM Alejandro Garnacho | AM Amad Diallo
ST Rasmus Højlund
Injury/suspension updates:
Jonny Evans, D, undisclosed, DOUBT
Mason Mount, F/M, strain, DOUBT
Marcus Rashford, F, personal, DOUBT
Luke Shaw, D, calf, DOUBT
Latest Crystal Palace team news
Expected Lineup:
GK Dean Henderson
CB Marc Guéhi | CB Maxence Lacroix | CB Chris Richards
LM Tyrick Mitchell | CM Will Hughes | CM Jefferson Lerma | RM Daniel Muñoz
AM Eberechi Eze | AM Ismaïla Sarr
ST Jean-Philippe Mateta
Injury/suspension updates:
Cheick Doucoure, M, knee, DOUBT
Matheus França, F/M, groin, DOUBT
Chadi Riad, D, knee, DOUBT
Chris Richards, D, head, DOUBT
Joel Ward, D, calf, DOUBT
Adam Wharton, M, groin, OUT, estimated return Feb. 15
Arsenal v Manchester City
Emirates Stadium
Sunday, 4:30 p.m. GMT / 11:30 a.m. ET
Latest Arsenal team news
Expected Lineup:
GK David Raya
LB Riccardo Calafiori | CB Gabriel Magalhães | CB William Saliba | RB Jurriën Timber
CM Martin Ødegaard | CM Declan Rice | CM Thomas Partey
FWL Leandro Trossard | ST Kai Havertz | FWR Gabriel Martinelli
Injury/suspension updates:
Gabriel Jesus, F, knee, OUT, estimated return Oct. 1
Bukayo Saka, F/M, hamstring, OUT, estimated return Mar. 8
Takehiro Tomiyasu, D, knee, OUT, estimated return Feb. 15
Ben White, D, knee, OUT, estimated return Feb. 15
Latest Manchester City team news
Expected Lineup:
GK Ederson
LB Josko Gvardiol | CB Manuel Akanji | CB John Stones | RB Matheus Nunes
CM Bernardo Silva | CM Ilkay Gündogan | CM Mateo Kovacic
FWL Omar Marmoush | ST Erling Haaland | FWR Phil Foden
Injury/suspension updates:
Nathan Aké, D, undisclosed, OUT, estimated return Feb. 11
Oscar Bobb, F/M, leg, DOUBT
Rúben Dias, D, groin, OUT, estimated return Feb. 15
Jérémy Doku, F/M, undisclosed, OUT, estimated return Feb. 11
Rodri, M, knee, OUT, estimated return Jul. 1
Chelsea v West Ham United
Stamford Bridge
Monday, 8 p.m. GMT / 3 p.m. ET
Latest Chelsea team news
Expected Lineup:
GK Robert Sánchez
LB Marc Cucurella | CB Trevoh Chalobah | CB Levi Colwill | RB Reece James
DM Moisés Caicedo | DM Enzo Fernández
LW Jadon Sancho | AM Cole Palmer | RW Noni Madueke
ST Nicolas Jackson
Injury/suspension updates:
Benoît Badiashile, D, undisclosed, OUT, estimated return Feb. 22
Wesley Fofana, D, hamstring, OUT, estimated return Feb. 22
Romeo Lavia, M, undisclosed, OUT, estimated return Feb. 14
Mykhailo Mudryk, F/M, suspension, due back Feb. 25
Gaga Slonina, G, finger, OUT, estimated return Feb. 22
Latest West Ham United team news
Expected Lineup:
GK Alphonse Areola
CB Vladimír Coufal | CB Aaron Cresswell | CB Max Kilman
LM Emerson | CM Edson Álvarez | CM Tomás Soucek | RM Aaron Wan-Bissaka
AM Mohammed Kudus | AM Carlos Soler
ST Lucas Paquetá
Injury/suspension updates:
Michail Antonio, F, leg, OUT, estimated return Dec. 1
Jarrod Bowen, F/M, foot, DOUBT
Niclas Füllkrug, F, hamstring, OUT, estimated return Feb. 22
Lucas Paquetá, F/M, groin, DOUBT
Crysencio Summerville, F/M, hamstring, DOUBT
Jean-Clair Todibo, D, undisclosed, DOUBT