- Javier Parraguez (12', 45'+1')
- Gabriel (80')
Estadio Monumental David Arellano
9:00 PM, 6 November 2021
Match ends, Colo-Colo 3, Santiago Wanderers 0.
Second Half ends, Colo-Colo 3, Santiago Wanderers 0.
VAR Decision: No Goal Colo-Colo 3-0 Santiago Wanderers.
Colo-Colo avoid first relegation in 96-year history of club
Chilean side Colo-Colo avoided relegation for the first time in the club's 96-year history with a 1-0 win at Universidad Concepcion.
'Win or we kill you' - Ultras prepare for Colo-Colo relegation decider
A banner with death threats aimed at players of Chilean club Colo-Colo was displayed at the club's training ground.