LA Galaxy II's scheduled match with San Diego Loyal SC on Wednesday was postponed due to a number of positive coronavirus tests, the club announced.
A team source told ESPN's Jeff Carlisle on Thursday that 11 Galaxy II players had tested positive.
The USL Championship clash was due to take place at Dignity Health Sports Park in Carson, Calif., but will now be played at a later date.
A club statement on Wednesday read: "LA Galaxy II's match vs. San Diego Loyal SC scheduled for tonight at 7 p.m. PT at Dignity Health Sports Park has been postponed and will be rescheduled at a later date.
"Proceeding with an abundance of caution, the postponement comes after covered individuals scheduled to be involved in tonight's match tested positive for COVID-19, as part of weekly routine testing."
LA Galaxy II are the reserve side of MLS team LA Galaxy, who were knocked out of the MLS is Back tournament after finishing bottom of Group F, losing two of their three matches.
No players from the Galaxy senior squad, who are back in Los Angeles, have tested positive, the source added.
San Diego Loyal are coached by former United States and Galaxy great Landon Donovan.