Atletico Madrid's Luis Suarez struck two late goals to give the LaLiga champions a 2-1 win at Getafe on Tuesday.
Memphis Depay struck the winning goal as Barcelona maintained their unbeaten start to the season with a 2-1 win against Getafe.
Erik Lamela continued his flying start to life with Sevilla, striking a last-minute winner for a 1-0 victory over Getafe.
A coolly taken penalty by Carlos Soler gave 10-man Valencia a 1-0 win over Getafe after the home side had defender Hugo Guillamon sent off.
Lionel Messi scored two first-half goals as Barcelona defeated Getafe to stay alive in the La Liga title race.
A heavily depleted Real Madrid side scraped a 0-0 draw at Getafe on Sunday in La Liga to fall three points behind leaders Atletico Madrid.
La Liga leaders Atletico Madrid drew 0-0 away to struggling Getafe on Saturday, despite playing the latter stages of the game with an extra man.
Valencia's Gabriel Paulista broke down in tears during a post-match interview on Saturday when it was suggested his side were in a relegation fight.
Real Madrid scored twice in the second half through Karim Benzema and Ferland Mendy to beat Getafe 2-0 and pick up an important three points.
Sevilla overcame a serious-looking injury to talisman Lucas Ocampos to beat Getafe 3-0 in La Liga on Saturday.
As every elite soccer club searches for an edge, the use of algorithms to predict player injuries could be the next frontier.
A Luis Suarez header gave Atletico Madrid a 1-0 home win over Getafe on Wednesday in coach Diego Simeone's 500th game in charge of the club.