- Cyle Larin (42' Pen)
- Sergio Escudero (74')
- Nahuel Molina (20')
- José María Giménez (24')
- Álvaro Morata (38')
- Joaquín (86' OG)
- Memphis Depay (90'+3')
Nahuel Molina, Jose Maria Gimenez and Alvaro Morata were all on target for Atletico in the first half while an own goal from Joaquin and Memphis Depay added to their tally late on after Valladolid had fought back to 3-2.
With six games to play, third-placed Atletico climbed to 66 points, closing the gap to Real, who won 4-2 against lowly Almeria on Saturday. Barcelona, top with 79 points, moved a step closer to their 27th LaLiga title with a 4-0 win over Real Betis on Saturday.
Defender Molina opened the scoring for visitors Atletico in the 20th minute with a close-range strike from a counter-attack and Gimenez extended their lead four minutes later with a towering header from a free kick by Antoine Griezmann.
Morata scored the third with a tap-in from another Griezmann cross in the 38th, but Valladolid battled back, scoring their first from the penalty spot through Cyle Larin after Mario Hermoso fouled Gonzalo Plata inside the box.
Sergio Escudero scored Valladolid's second in the 74th minute with a header from a corner, but Atletico kept their cool and scored their fourth 12 minutes later, with Joaquin netting an own goal after trying to clear a cross from Angel Correa.
Depay secured Atletico's eighth win in their last nine league games with a brilliant individual goal in added time, dribbling past three defenders before scoring with a tidy finish from a counter-attack.
- Antonio Miguel Mateu Lahoz