Araujo is one of a number of youngsters and newcomers in the 23-player squad who will look to impress Mexico manager Gerardo "Tata" Martino.
The 20-year-old Araujo has dual-nationality and represented the United States at youth level. He was a member of the provisional 2021 Gold Cup roster for the senior U.S. squad. USMNT manager Gregg Berhalter said in the summer that Araujo was "not ready to fully commit to the team" after he had made himself unavailable for selection for the Gold Cup.
In October, the right-back announced that he had made the switch to Mexico.
Fellow Galaxy teammate Efrain Alvarez has also been included in Mexico's squad. Like Araujo, Alvarez switched to Mexico from the U.S. and made his senior debut for Martino during a friendly in March.
Another notable inclusion to Mexico's squad is Arsenal youngster Marcelo Flores, who is also eligible to represent Canada and England. Flores, 18, had been cleared by the Premier League club to join the El Tri camp last week. The attacking midfielder was included in Canada's provisional squad for the 2021 Gold Cup, but took part in the Revelations Cup tournament last month with Mexico's youth national team. He has yet to make a senior debut for any squad.
Mexico also included Union Espanola's Benjamin Galdames to the squad. The 20-year-old midfielder is the son of former Chile international Pablo Galdames and eligible to play for both nations.
Other players who could earn their first senior cap for Mexico include: Emilio Lara, Mauro Lainez, Salvador Reyes, Israel Reyes, Omar Campos, Carlos Acevedo, Luis Malagon, and Luis Olivas.
The upcoming match will be Mexico's first trip to Austin's Q2 Stadium, and Mexico will look to close out the year with a win after losing to the USMNT and Canada in November during CONCACAF's Octagonal round of World Cup qualifying.
GOALKEEPERS: Alfredo Talavera (Pumas UNAM), Carlos Acevedo (Santos Laguna), Luis Malagon (Necaxa)
DEFENDERS: Julian Araujo (LA Galaxy), Emilio Lara, Salvador Reyes (America), Jordan Silva (America), Luis Olivas (Guadalajara), Israel Reyes (Puebla)
MIDFIELDERS: Erik Lira (Pumas UNAM), Erick Aguirre (Monterrey), Alfonso Gonzalez (Monterrey), Uriel Antuna (Guadalajara), Fernando Beltran (Guadalajara), Omar Campos (Santos Laguna), Alan Cervantes (Santos Laguna), Sebastian Cordova (America), Marcelo Flores (Arsenal)
FORWARDS: Eduardo Aguirre (Santos Laguna), Benjamin Galdames (Union Espanola), Santiago Gimenez (Cruz Azul), Mauro Lainez (America), Efrain Alvarez (LA Galaxy)