With four players each from Barcelona and Real Madrid, the Spanish giants combined to put eight players on the 2015 FIFPro World XI.
The team, announced on Monday at the Ballon d'Or ceremony in Zurich, featured Lionel Messi, Neymar, Dani Alves and Andres Iniesta from Barcelona, while Cristiano Ronaldo, Marcelo, Sergio Ramos and Luka Modric represented Real Madrid.
Also on the team were Paul Pogba of Juventus, Paris Saint-Germain's Thiago Silva and Bayern Munich goalkeeper Manuel Neuer.
Messi and Ronaldo both made the XI for the ninth time in their careers, the most appearances of any players. Iniesta is next on that list with his seventh appearance on the team.
Neuer made the team for the third straight season, while Neymar, Modric and Pogba all made their debuts.
Barcelona's Luis Suarez was again left off the list, while Real Madid's Gareth Bale and James Rodriguez are also left waiting for their names to be called for the first time.
Over the last six seasons, 47 of the 66 players selected to the World's eleven best players have come from La Liga, 40 more than the Bundesliga, the next most-represented league.
England's Premier League was the only one of Europe's five major leagues not to be represented on the team, which is made up from 45,000 ballots by professional players from countries whose national associations are FIFPro members.
2015 FIFPro World XI
Goalkeeper: Manuel Neuer (Bayern Munich, Germany)
Defenders: Thiago Silva (Paris Saint-Germain, Brazil), Marcelo (Real Madrid, Brazil), Sergio Ramos (Real Madrid, Spain), Dani Alves (Barcelona, Brazil)
Midfielders: Andres Iniesta (Barcelona, Spain), Luka Modric (Real Madrid, Croatia), Paul Pogba (Juventus, France)
Forwards: Neymar (Barcelona, Brazil), Lionel Messi (Barcelona, Argentina), Cristiano Ronaldo (Real Madrid, Portugal)